• Controlling light for in-vivo deep tissue imaging

  • Speaker : 박정훈/ Jung-Hoon Park
    Affiliation : Department of Biomedical Engineering, UNIST
    Date : May 30, 2018 4:00 PM
    Place : Building 110 Room N103
    Contact :
    Host : 정준우
  • Abstract

  • Throughout the history of science, the development of new imaging technologies has often been followed by new discoveries in the mechanisms of life. Along this line, impressive advances in improving the spatiotemporal resolution and developing novel contrast mechanisms for bio imaging has been continuously going underway during the past century. However, most advanced imaging technologies to date are only suitable for transparent subjects or single cells limiting their application to the observation of biological processes in an artificial, and often 2D, environment. By controlling the properties of light however, we can design specific light beams that can penetrate more deeply and focus more tightly even in the most turbid biological structures. This becomes possible by measuring the tissue induced aberrations on the optical wavefront and compensating for the aberration using wavefront modulation schemes. Along this line, we will discuss our recent approaches to enable fast high resolution imaging inside deep tissue, the limitations we still face, future steps to overcome these barriers and the biological problems we hope to solve using this newly developed technology.