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People

Professor
People

Professor

Tlusty Tsvi트룰스티 츠비

  • protein evolution
  • dimensional reduction
  • active matter
  • Molecular recognition
  • chemotaxis
  • fluorescence correlation spectroscopy

연구주제

Living matter/nonequilibrium physics/soft matter

  • 연구분야Systems biology ; Physical biology ; Molecular information
  • 연구실Living Matter Theory

Current Research Interests

  • Our research is at the nexus of non-equilibrium physics, biochemistry, and living matter.
  • We study fundamental questions in living and soft matter using physical and mathematical approaches.
  • Current subjects include:
  • 1) Physics of protein machines.
  • 2) Quantum concepts in dissipative classic systems.
  • 3) Hirerchical organization of living matter.
  • For further details see our publications.

Biographical Sketch

  • 2015– : Distinguished Professor, Department of Physics, UNIST, Ulsan
  • 2015–2024: PI, Center for Soft and Living Matte, Institute for Basic Science.
  • 2011–2015: Long-term Member, Institute of Advanced Study, Princeton.
  • 2005–2013: Senior researcher, Physics of Complex Systems, Weizmann Institute.
  • 2000–2004: Fellow, Center for Physics and Biology, Rockefeller University, New York.
  • 1995–2000: Ph.D. in Physics, Weizmann Institute, “Universality in Microemulsions”, Supervisor: Samuel A. Safran.
  • 1991–1995: M.Sc. in Physics, Weizmann Institute.
  • 1988–1990: B.Sc. in Physics and Mathematics, Hebrew University, Jerusalem.

Selected Publications

  • Weinreb EM, McBride JM... J-P, Moses, E &Tlusty T (2025) High-shear regions in an enzyme impact viscoelastic mechanics and activity. Nature Physics 21(5): 787-798.
  • Libchaber A, Tlusty T (2025) Life sets off a cascade of machines. Proc Nat Acad Sci USA, 122 (4) e2418000122.
  • McBride JM & Tlusty T (2024) AI-Predicted Protein Deformation Encodes Energy Landscape Perturbation. Physical Review Letters 133, 098401.
  • McBride JM, ... Tlusty T (2023) AlphaFold2 Can Predict Single-Mutation Effects. Physical Review Letters 131(21):218401.
  • Saeed I, Pak HK, & Tlusty T (2023) Quasiparticles, flat bands and the melting of hydrodynamic matter. Nature Physics 19(4):536-544.
  • Mani S & Tlusty T (2023) Gene birth in a model of non-genic adaptation. BMC Biology 21(1):257.
  • Tripathi AK & Tlusty T (2022) Gauging Nanoswimmer Dynamics via the Motion of Large Bodies. Physical Review Letters 129(25):254502.
  • Pineros WD & Tlusty T (2022) Spontaneous chiral symmetry breaking in a random driven chemical system. Nature Commun 13(1):2244.
  • Paneru G, Dutta S, Sagawa T, Tlusty T, & Pak HK (2020) Efficiency fluctuations and noise-induced refrigerator-to-heater transition in information engines. Nature Communications 11(1):1012.
  • Eckmann J-P, Rougemont J, & Tlusty T (2019) Proteins: The physics of amorphous evolving matter. Reviews of Modern Physics 91(3):031001.
  • Paneru G, Lee DY, Tlusty T, & Pak HK (2018) Lossless Brownian Information Engine. Physical Review Letters 120(2):020601.
  • Jee AY, Cho YK, Granick S, & Tlusty T (2018) Catalytic enzymes are active matter. Proc Nat Acad Sci USA 115(46):E10812-E10821.
  • Tlusty T Libchaber A & Eckmann JP (2017) Physical model of the sequence-to-function map of proteins, Physical Review X, 7(2): 021037.
  • Shani I, Beatus T, Bar-Ziv R. & Tlusty T (2014) Long-range orientational order in 2D microfluidic dipoles. Nature Physics 10 (2): 140-144.
  • Savir Y& Tlusty T. (2013) The ribosome as an optimal decoder: a lesson in molecular recognition. Cell 153(2):471-479.

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